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Estados Unidos – 14/Ene/2022
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La esclerosis múltiple, una enfermedad progresiva para la que no hay una cura definitiva, «está probablemente» causada por la infección con el virus de Epstein-Barr, que provoca la mononucleosis, según un gran estudio de veinte años, que publica hoy Science.
La investigación liderada por la Universidad de Harvard, siguió a más de diez millones de reclutas militares en Estados Unidos e identificó a 955 que fueron diagnosticados de esclerosis múltiple durante su periodo de servicio.
La hipótesis de que el virus de Epstein-Barr (VEB) cause la esclerosis múltiple ha sido analizada por diversos grupos científicos durante varios años, pero “este es el primer estudio que aporta pruebas convincentes de causalidad», según el autor principal de la investigación, Alberto Ascherio, de la Escuela de Salud Pública T.H. Chan de Harvard.
El científico consideró que se trata “de un gran paso, porque sugiere que la mayoría” de los casos de esclerosis múltiple (EM) “podrían prevenirse deteniendo la infección” por el virus que causa la mononucleosis, conocida como la enfermedad del beso, y que tener el virus de Epstein-Barr como objetivo “podría conducir al descubrimiento de una cura para la EM».
La esclerosis múltiple, que afecta a 2,8 millones de personas en el mundo, es una enfermedad inflamatoria crónica del sistema nervioso central que ataca las vainas de mielina que protegen las neuronas del cerebro y la médula espinal.
Aunque no se conoce su causa, uno de los principales sospechosos es el VEB, un virus herpes que puede causar mononucleosis infecciosa y que establece una infección latente y de por vida en el huésped.
En la actualidad no hay forma de prevenir o tratar eficazmente la infección por el virus de Epstein-Barr, pero una vacuna contra este o atacarlo con fármacos antivirales específicos “podría, en última instancia, prevenir o curar la esclerosis múltiple», agregó el experto.
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